Drawing on more than three decades of clinical and research experience, Dr. Nikolaos Pandis explores the central role of evidence-based medicine in orthodontic clinical decision-making. He emphasizes that clinicians should move beyond relying solely on personal experience, expert opinion, or marketing-driven information, and overcome common “decision-making dilemmas” by integrating clinical expertise, best research evidence, and patient values to establish a more scientific and evidence-based approach to clinical care.

As Editor-in-Chief of Progress in Orthodontics, Dr. Nikolaos Pandis will examine the principles of clinical research design, reporting standards, and common pitfalls in scientific publication. Using the EQUATOR Network reporting guidelines as a practical framework, he outlines the publication process of a research paper and guides participants step by step in improving study design and manuscript quality — from title writing and figure presentation to data reporting and annotation standards.