This course explores core strategies in combined orthodontic–orthognathic treatment, focusing on two highly challenging clinical scenarios in skeletal malocclusion: surgery-first treatment for skeletal facial asymmetry and secondary orthodontic–orthognathic treatment after failed camouflage orthodontics. The first part focuses on the surgery-first approach for skeletal asymmetry. It covers how to accurately determine the final occlusal plane before surgery, align the facial and skeletal midlines, ensure rapid postoperative orthodontic coordination, and manage complex factors such as soft tissue fillers and muscle memory.

As Editor-in-Chief of Progress in Orthodontics, Dr. Nikolaos Pandis will examine the principles of clinical research design, reporting standards, and common pitfalls in scientific publication. Using the EQUATOR Network reporting guidelines as a practical framework, he outlines the publication process of a research paper and guides participants step by step in improving study design and manuscript quality — from title writing and figure presentation to data reporting and annotation standards.

Drawing on more than three decades of clinical and research experience, Dr. Nikolaos Pandis explores the central role of evidence-based medicine in orthodontic clinical decision-making. He emphasizes that clinicians should move beyond relying solely on personal experience, expert opinion, or marketing-driven information, and overcome common “decision-making dilemmas” by integrating clinical expertise, best research evidence, and patient values to establish a more scientific and evidence-based approach to clinical care.

This course provides a comprehensive exploration of contemporary orthodontic treatment strategies, focusing on two critical areas of clinical practice: transverse management and vertical management. The first part of the program focuses on transverse management, specifically addressing the early interceptive treatment of posterior crossbite in the mixed dentition. You will explore evidence-based comparisons of treatment modalities with a focus on their skeletal and dental effects, patient-reported pain and discomfort, anchorage strategies (including the use of primary teeth and mini-screws), and cost-effectiveness.